BAIT
CSNK1E
AI426939, AI551861, AW457082, CK1epsilon, CKIe, KC1epsilon, tau, RP23-120A4.1
casein kinase 1, epsilon
GO Process (11)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- cellular protein localization [IDA]
- circadian regulation of gene expression [IMP]
- circadian rhythm [TAS]
- endocytosis [IBA]
- negative regulation of Wnt signaling pathway [IGI]
- peptidyl-serine phosphorylation [IBA]
- positive regulation of canonical Wnt signaling pathway [IGI]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- protein phosphorylation [IDA, IMP, ISO]
- regulation of cell shape [IBA]
- regulation of circadian rhythm [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
PER2
FASPS, FASPS1
period circadian clock 2
GO Process (22)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- circadian regulation of gene expression [ISS]
- circadian regulation of translation [ISS]
- circadian rhythm [TAS]
- fatty acid metabolic process [ISS]
- gluconeogenesis [ISS]
- glycogen biosynthetic process [ISS]
- histone H3 deacetylation [ISS]
- lactate biosynthetic process [ISS]
- negative regulation of circadian rhythm [ISS]
- negative regulation of fat cell proliferation [ISS]
- negative regulation of protein ubiquitination [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- negative regulation of transcription regulatory region DNA binding [ISS]
- negative regulation of transcription, DNA-templated [ISS]
- regulation of cell cycle [ISS]
- regulation of circadian rhythm [ISS]
- regulation of glutamate uptake involved in transmission of nerve impulse [ISS]
- regulation of insulin secretion [ISS]
- regulation of neurogenesis [ISS]
- regulation of vasoconstriction [ISS]
- response to ischemia [ISS]
- white fat cell differentiation [ISS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID