BAIT
DDB1
127kDa, AA408517, p127-Ddb1
damage specific DNA binding protein 1
GO Process (8)
GO Function (1)
GO Component (9)
Gene Ontology Biological Process
- UV-damage excision repair [ISO]
- Wnt signaling pathway [IDA]
- histone H2A monoubiquitination [ISO]
- negative regulation of apoptotic process [IMP]
- nucleotide-excision repair [IBA]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA, ISO]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISO]
- regulation of mitotic cell cycle phase transition [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PHGDH
3-PGDH, 3PGDH, HEL-S-113, NLS, NLS1, PDG, PGAD, PGD, PGDH, PHGDHD, SERA, RP4-683H9.1
phosphoglycerate dehydrogenase
GO Process (5)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID