BAIT
CCT3
AL024092, Cctg, Tcp1-rs3, TriC-P5
chaperonin containing Tcp1, subunit 3 (gamma)
GO Process (3)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
IGBP1
ALPHA-4, IBP1, RP13-46G5.1
immunoglobulin (CD79A) binding protein 1
GO Process (7)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of stress-activated MAPK cascade [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of microtubule-based movement [IMP]
- response to interleukin-1 [IMP]
- response to tumor necrosis factor [IMP]
- signal transduction [NAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID