CENPE
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- attachment of mitotic spindle microtubules to kinetochore [ISO]
- attachment of spindle microtubules to kinetochore [IMP, TAS]
- establishment of protein localization [IMP]
- metabolic process [ISO]
- microtubule-based movement [IBA]
- mitotic metaphase plate congression [ISO]
- mitotic spindle assembly checkpoint [IMP]
- positive regulation of attachment of spindle microtubules to kinetochore [IMP]
- positive regulation of chromosome segregation [IMP]
- positive regulation of mitotic metaphase/anaphase transition [IMP]
- positive regulation of protein kinase activity [IDA, ISO]
- regulation of developmental process [IMP]
- regulation of mitosis [IMP]
- regulation of mitotic metaphase/anaphase transition [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell [IMP]
- chromosome [ISO]
- chromosome, centromeric region [ISO]
- condensed chromosome outer kinetochore [IDA]
- condensed chromosome, centromeric region [ISO]
- condensed nuclear chromosome kinetochore [IDA]
- cytoplasm [ISO]
- kinesin complex [IBA]
- kinetochore [IDA, ISO]
- membrane [ISO]
- microtubule [ISO]
- microtubule cytoskeleton [ISO]
- midbody [ISO]
- mitotic spindle midzone [ISO]
- nucleus [ISO]
CLASP2
Gene Ontology Biological Process
- axon guidance [TAS]
- establishment or maintenance of cell polarity [TAS]
- fucosylation [NAS]
- microtubule anchoring [IMP]
- microtubule nucleation [IMP]
- microtubule organizing center organization [IMP]
- mitotic cell cycle [TAS]
- negative regulation of microtubule depolymerization [NAS]
- regulation of microtubule polymerization or depolymerization [IMP]
- regulation of microtubule-based process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CENPE CLASP2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 1466313 |
Curated By
- BioGRID