BAIT

SGOL1

3300001M08Rik, C81037, Sgo1

shugoshin-like 1 (S. pombe)

GO Process (4)

GO Function (1)

GO Component (9)

Gene Ontology Biological Process

attachment of spindle microtubules to kinetochore [ISO]

centriole-centriole cohesion [IMP, ISO]

chromosome segregation [ISO]

meiotic chromosome segregation [ISO]

Gene Ontology Molecular Function

kinase binding [ISO]

Gene Ontology Cellular Component

centrosome [ISO]

chromosome, centromeric region [IDA, ISO]

condensed chromosome, centromeric region [ISO]

condensed nuclear chromosome, centromeric region [IDA]

cytoplasm [ISO]

kinetochore [IDA, ISO]

mitotic cohesin complex [ISO]

nucleoplasm [ISO]

spindle pole [ISO]

CRISPR Database MGI Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Mus musculus

PREY

PPP2R5D

B56D

protein phosphatase 2, regulatory subunit B', delta

Alzheimer's Disease Project

Autism spectrum disorder (ASD) Project

GO Process (23)

GO Function (2)

GO Component (3)

Gene Ontology Biological Process

MyD88-dependent toll-like receptor signaling pathway [TAS]

MyD88-independent toll-like receptor signaling pathway [TAS]

TRIF-dependent toll-like receptor signaling pathway [TAS]

carbohydrate metabolic process [TAS]

dephosphorylation [TAS]

energy reserve metabolic process [TAS]

glucose metabolic process [TAS]

glycolytic process [TAS]

innate immune response [TAS]

nervous system development [TAS]

neurotrophin TRK receptor signaling pathway [TAS]

regulation of catalytic activity [TAS]

small molecule metabolic process [TAS]

stress-activated MAPK cascade [TAS]

toll-like receptor 10 signaling pathway [TAS]

toll-like receptor 2 signaling pathway [TAS]

toll-like receptor 3 signaling pathway [TAS]

toll-like receptor 4 signaling pathway [TAS]

toll-like receptor 5 signaling pathway [TAS]

toll-like receptor 9 signaling pathway [TAS]

toll-like receptor TLR1:TLR2 signaling pathway [TAS]

toll-like receptor TLR6:TLR2 signaling pathway [TAS]

toll-like receptor signaling pathway [TAS]

Gene Ontology Molecular Function

protein binding [IPI]
protein serine/threonine phosphatase activity [TAS]

Gene Ontology Cellular Component

nucleoplasm [TAS]

CRISPR Database HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

Hutchins JR, Toyoda Y, Hegemann B, Poser I, Heriche JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM

Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]

Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]

Throughput

High Throughput

Curated By

BioGRID