CAMK4
Gene Ontology Biological Process
- activation of phospholipase C activity [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- long-term memory [IGI]
- myeloid dendritic cell cytokine production [IMP]
- myeloid dendritic cell differentiation [IMP]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of T cell differentiation in thymus [TAS]
- regulation of osteoclast differentiation [TAS]
- signal transduction [TAS]
- synaptic transmission [TAS]
Gene Ontology Cellular Component
CABIN1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Biochemical Activity (Phosphorylation)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation.
Calcium signaling is critical for activation of T lymphocytes and has been proposed to be transduced through multiple calmodulin target proteins. Whereas the calcineurin-NFAT signaling module is critical for all mammalian T cells, the role of calmodulin-dependent kinase IV (CaMKIV) in mouse naive CD4+ T-cell activation remains enigmatic. We have applied lentivius-mediated RNA interference of CaMKIV to human T cells ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID