BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SDCBP
MDA-9, Sycl, syntenin-1, RP23-89L15.4
syndecan binding protein
GO Process (4)
GO Function (14)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function- cell adhesion molecule binding [ISO]
- ephrin receptor binding [ISO]
- frizzled binding [ISO]
- glycoprotein binding [ISO]
- growth factor binding [ISO]
- identical protein binding [ISO]
- interleukin-5 receptor binding [IMP]
- neurexin family protein binding [ISO]
- protein C-terminus binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- syndecan binding [ISO]
- cell adhesion molecule binding [ISO]
- ephrin receptor binding [ISO]
- frizzled binding [ISO]
- glycoprotein binding [ISO]
- growth factor binding [ISO]
- identical protein binding [ISO]
- interleukin-5 receptor binding [IMP]
- neurexin family protein binding [ISO]
- protein C-terminus binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- syndecan binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
MDA-9/syntenin interacts with ubiquitin via a novel ubiquitin-binding motif.
Ubiquitination appears to be involved in proteasome-dependent proteolysis and in the membrane trafficking system including endocytosis and exocytosis. In this study, we identified MDA-9/syntenin as a novel ubiquitin-binding protein by a yeast two-hybrid system using modified ubiquitin in which lysine 48 is substituted by arginine. It has been reported that MDA-9/syntenin is a membrane-associated protein and regulates a cellular process ... [more]
Mol. Cell. Biochem. Jun. 01, 2011; 352(1);163-72 [Pubmed: 21359963]
Throughput
- Low Throughput
Additional Notes
- #LPPI
- Likely protein-protein interaction
Curated By
- BioGRID