BAIT

PLEKHO1

CKIP-1, OC120, RP11-458I7.3
pleckstrin homology domain containing, family O member 1
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens
PREY

DNAJB1

HSPF1, Hdj1, Hsp40, RSPH16B, Sis1
DnaJ (Hsp40) homolog, subfamily B, member 1
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways.

Wang J, Yuan Y, Zhou Y, Guo L, Zhang L, Kuai X, Deng B, Pan Z, Li D, He F

The Ras-MAPK and PI3K-AKT pathways are conserved in metazoan organisms, which involve a series of signaling cascades and form the basis for numerous physiological and pathological processes. Here we report on yeast two hybrid screening results of a protein interaction network around the known components of human Ras-MAPK/PI3K pathways. A total of 42 independent cDNA library screenings resulted in 200 ... [more]

J. Proteome Res. Sep. 01, 2008; 7(9);3879-89 [Pubmed: 18624398]

Throughput

  • Low Throughput

Curated By

  • BioGRID