BAIT
TNFRSF21
BM-018, CD358, DR6, UNQ437/PRO868
tumor necrosis factor receptor superfamily, member 21
GO Process (18)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- B cell apoptotic process [ISS]
- T cell receptor signaling pathway [ISS]
- adaptive immune response [ISS]
- apoptotic process [IMP]
- cellular lipid metabolic process [TAS]
- cellular response to tumor necrosis factor [IDA]
- humoral immune response [ISS]
- myelination [ISS]
- negative regulation of B cell proliferation [ISS]
- negative regulation of T cell proliferation [ISS]
- negative regulation of interleukin-10 secretion [ISS]
- negative regulation of interleukin-13 secretion [ISS]
- negative regulation of interleukin-5 secretion [ISS]
- negative regulation of myelination [IMP]
- neuron apoptotic process [ISS]
- oligodendrocyte apoptotic process [ISS]
- regulation of oligodendrocyte differentiation [ISS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
STX11
FHL4, HLH4, HPLH4
syntaxin 11
GO Process (4)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID