BAIT
UBE3A
ANCR, AS, E6-AP, EPVE6AP, HPVE6A
ubiquitin protein ligase E3A
GO Process (9)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- androgen receptor signaling pathway [IBA]
- brain development [TAS]
- protein K48-linked ubiquitination [IDA]
- protein autoubiquitination [IDA]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IBA]
- proteolysis [TAS]
- regulation of circadian rhythm [IMP]
- regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IMP]
- ubiquitin-dependent protein catabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
PDE1B
PDE1B1, PDES1B
phosphodiesterase 1B, calmodulin-dependent
GO Process (13)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- activation of phospholipase C activity [TAS]
- apoptotic process [TAS]
- blood coagulation [TAS]
- cAMP catabolic process [IDA]
- cGMP catabolic process [IDA]
- cellular response to granulocyte macrophage colony-stimulating factor stimulus [IDA]
- cellular response to macrophage colony-stimulating factor stimulus [IDA]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- monocyte differentiation [IEP]
- neurotrophin TRK receptor signaling pathway [TAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID