BAIT

TAF1D

JOSD3, RAFI41, TAF(I)41, TAFI41

TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa

GO Process (5)

GO Function (1)

GO Component (2)

Gene Ontology Biological Process

gene expression [TAS]

termination of RNA polymerase I transcription [TAS]

transcription elongation from RNA polymerase I promoter [TAS]

transcription from RNA polymerase I promoter [TAS]

transcription initiation from RNA polymerase I promoter [TAS]

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

microtubule organizing center [IDA]

nucleoplasm [IDA, TAS]

CRISPR Database OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Homo sapiens

PREY

HSP90AB1

D6S182, HSP84, HSP90B, HSPC2, HSPCB, RP1-302G2.1

heat shock protein 90kDa alpha (cytosolic), class B member 1

Alzheimer's Disease Project

GO Process (9)

GO Function (7)

GO Component (6)

Gene Ontology Biological Process

Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]

axon guidance [TAS]

innate immune response [TAS]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [TAS]

positive regulation of nitric oxide biosynthetic process [ISS]

regulation of interferon-gamma-mediated signaling pathway [IMP]

regulation of type I interferon-mediated signaling pathway [IMP]

response to unfolded protein [NAS]

Gene Ontology Molecular Function

MHC class II protein complex binding [IDA]
TPR domain binding [ISS]
double-stranded RNA binding [IDA]
kinase binding [IPI]
nitric-oxide synthase regulator activity [ISS]
poly(A) RNA binding [IDA]
protein binding [IPI]

Gene Ontology Cellular Component

COP9 signalosome [IDA]

cytoplasm [IDA]

extracellular vesicular exosome [IDA]

mitochondrion [IDA]

CRISPR Database OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A directed protein interaction network for investigating intracellular signal transduction.

Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro MA, Wanker EE

Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]

Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]

Throughput

High Throughput

Curated By

BioGRID