BAIT
MEST
PEG1
mesoderm specific transcript
GO Process (1)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
BLOC1S2
BLOS2, CEAP, CEAP11, RP11-316M21.4
biogenesis of lysosomal organelles complex-1, subunit 2
GO Process (11)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- anterograde axon cargo transport [ISS]
- anterograde synaptic vesicle transport [ISS]
- extrinsic apoptotic signaling pathway via death domain receptors [IDA]
- melanosome organization [NAS]
- microtubule nucleation [NAS]
- mitochondrial outer membrane permeabilization [IDA]
- neuron projection development [ISS]
- platelet dense granule organization [NAS]
- positive regulation of cell proliferation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IBA]
- positive regulation of transcription, DNA-templated [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID