BAIT
CSNK2B
CK2B, CK2N, CSK2B, G5A, DADB-127H9.2
casein kinase 2, beta polypeptide
GO Process (13)
GO Function (7)
GO Component (7)
Gene Ontology Biological Process
- adiponectin-activated signaling pathway [IDA]
- axon guidance [TAS]
- cellular protein complex assembly [NAS]
- endothelial tube morphogenesis [IMP]
- mitotic cell cycle [TAS]
- negative regulation of blood vessel endothelial cell migration [IDA]
- negative regulation of cell proliferation [TAS]
- positive regulation of activin receptor signaling pathway [IMP]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IDA]
- protein phosphorylation [TAS]
- regulation of DNA binding [NAS]
- regulation of protein kinase activity [NAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CHRNA4
BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4
cholinergic receptor, nicotinic, alpha 4 (neuronal)
GO Process (21)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
- B cell activation [ISS]
- DNA repair [IMP]
- action potential [ISS]
- behavioral response to nicotine [IMP]
- calcium ion transport [ISS]
- cation transmembrane transport [IDA, TAS]
- cognition [IMP]
- ion transmembrane transport [TAS]
- ion transport [NAS]
- membrane depolarization [ISS]
- neurological system process [IMP]
- regulation of dopamine secretion [ISS]
- regulation of inhibitory postsynaptic membrane potential [ISS]
- regulation of membrane potential [ISS]
- response to hypoxia [IDA]
- response to nicotine [IDA]
- response to oxidative stress [IMP]
- sensory perception of pain [ISS]
- signal transduction [IDA]
- synaptic transmission [NAS, TAS]
- synaptic transmission, cholinergic [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID