BAIT
FES
FPS
FES proto-oncogene, tyrosine kinase
GO Process (22)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- axon guidance [TAS]
- cell migration [IBA]
- cell proliferation [TAS]
- chemotaxis [IBA]
- epidermal growth factor receptor signaling pathway [IBA]
- innate immune response [IBA]
- multicellular organismal development [TAS]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of actin cytoskeleton reorganization [IMP]
- positive regulation of microtubule polymerization [IMP]
- positive regulation of myeloid cell differentiation [IMP]
- positive regulation of neuron projection development [IMP]
- protein autophosphorylation [IDA]
- protein phosphorylation [TAS]
- regulation of cell adhesion [IMP]
- regulation of cell differentiation [IMP]
- regulation of cell motility [IMP]
- regulation of cell proliferation [IMP]
- regulation of cell shape [IMP]
- regulation of mast cell degranulation [IMP]
- regulation of vesicle-mediated transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ZNF746
PARIS
zinc finger protein 746
GO Process (4)
GO Function (6)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription regulatory region DNA binding [IDA]
- ubiquitin protein ligase binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription regulatory region DNA binding [IDA]
- ubiquitin protein ligase binding [IPI]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID