BAIT
TK1
TK2
thymidine kinase 1, soluble
GO Process (8)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
- deoxyribonucleoside monophosphate biosynthetic process [TAS]
- nucleobase-containing compound metabolic process [TAS]
- nucleobase-containing small molecule metabolic process [TAS]
- nucleotide biosynthetic process [EXP]
- protein homotetramerization [IPI]
- pyrimidine nucleobase metabolic process [TAS]
- pyrimidine nucleoside salvage [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
KIF5A
D12S1889, MY050, NKHC, SPG10
kinesin family member 5A
GO Process (9)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- axon guidance [IBA]
- blood coagulation [TAS]
- cytoskeleton-dependent intracellular transport [IBA]
- metabolic process [IBA, TAS]
- microtubule-based movement [IBA, TAS]
- protein localization [IBA]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID