BAIT
TK1
TK2
thymidine kinase 1, soluble
GO Process (8)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
- deoxyribonucleoside monophosphate biosynthetic process [TAS]
- nucleobase-containing compound metabolic process [TAS]
- nucleobase-containing small molecule metabolic process [TAS]
- nucleotide biosynthetic process [EXP]
- protein homotetramerization [IPI]
- pyrimidine nucleobase metabolic process [TAS]
- pyrimidine nucleoside salvage [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
EXT2
SOTV
exostosin glycosyltransferase 2
GO Process (9)
GO Function (7)
GO Component (6)
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- cellular polysaccharide biosynthetic process [IDA]
- glycosaminoglycan biosynthetic process [IDA, TAS]
- glycosaminoglycan metabolic process [TAS]
- heparan sulfate proteoglycan biosynthetic process [IMP]
- heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [IMP]
- ossification [IMP]
- signal transduction [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function- N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity [NAS]
- acetylglucosaminyltransferase activity [IDA]
- glucuronosyltransferase activity [IDA]
- heparan sulfate N-acetylglucosaminyltransferase activity [NAS]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IDA]
- transferase activity, transferring glycosyl groups [IDA]
- N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity [NAS]
- acetylglucosaminyltransferase activity [IDA]
- glucuronosyltransferase activity [IDA]
- heparan sulfate N-acetylglucosaminyltransferase activity [NAS]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IDA]
- transferase activity, transferring glycosyl groups [IDA]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID