BAIT
MAPK6
ERK3, HsT17250, PRKM6, p97MAPK
mitogen-activated protein kinase 6
GO Process (3)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
UBE2L3
E2-F1, L-UBC, UBCH7, UbcM4
ubiquitin-conjugating enzyme E2L 3
GO Process (12)
GO Function (8)
GO Component (4)
Gene Ontology Biological Process
- cell cycle phase transition [IMP]
- cell proliferation [IMP]
- cellular protein modification process [TAS]
- cellular response to glucocorticoid stimulus [IDA]
- cellular response to steroid hormone stimulus [IMP]
- positive regulation of protein ubiquitination [IGI]
- positive regulation of ubiquitin-protein transferase activity [IGI]
- protein K11-linked ubiquitination [IDA]
- protein polyubiquitination [IDA]
- protein ubiquitination [IDA]
- regulation of transcription, DNA-templated [IDA, IMP]
- ubiquitin-dependent protein catabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID