BAIT
CDC37
P50CDC37
cell division cycle 37
GO Process (6)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
SPTBN4
QV, SPNB4, SPTBN3
spectrin, beta, non-erythrocytic 4
GO Process (14)
GO Function (6)
GO Component (14)
Gene Ontology Biological Process
- adult walking behavior [ISS]
- axon guidance [TAS]
- axonogenesis [ISS]
- cardiac conduction [ISS]
- central nervous system projection neuron axonogenesis [ISS]
- clustering of voltage-gated sodium channels [ISS]
- cytoskeletal anchoring at plasma membrane [TAS]
- establishment of protein localization to plasma membrane [ISS]
- negative regulation of heart rate [ISS]
- regulation of peptidyl-serine phosphorylation [ISS]
- regulation of sodium ion transport [ISS]
- sensory perception of sound [ISS]
- transmission of nerve impulse [ISS]
- vesicle-mediated transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- PML body [IDA, ISS]
- adherens junction [ISS]
- axon hillock [ISS]
- axon initial segment [ISS]
- cell body fiber [ISS]
- cytoplasm [IDA, ISS]
- cytosol [TAS]
- extracellular vesicular exosome [IDA]
- membrane [IDA]
- neuronal cell body [ISS]
- node of Ranvier [ISS]
- nuclear matrix [IDA, ISS]
- plasma membrane [ISS]
- spectrin [IDA, ISS]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID