CDK4
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- mitotic cell cycle [TAS]
- negative regulation of cell cycle arrest [IDA]
- positive regulation of G2/M transition of mitotic cell cycle [IDA]
- positive regulation of cell proliferation [IMP]
- positive regulation of fibroblast proliferation [IMP]
- protein phosphorylation [IDA]
- regulation of gene expression [IMP]
- response to drug [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SETDB1
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CDK4 SETDB1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | 3 | BioGRID | - |
Curated By
- BioGRID