BAIT
RGS2
G0S8, GIG31
regulator of G-protein signaling 2
GO Process (8)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- negative regulation of G-protein coupled receptor protein signaling pathway [ISS]
- negative regulation of MAP kinase activity [ISS]
- negative regulation of cardiac muscle hypertrophy [ISS]
- negative regulation of phospholipase activity [ISS]
- positive regulation of cardiac muscle contraction [ISS]
- regulation of G-protein coupled receptor protein signaling pathway [TAS]
- regulation of adrenergic receptor signaling pathway [ISS]
- relaxation of cardiac muscle [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RAB2A
LHX, RAB2
RAB2A, member RAS oncogene family
GO Process (6)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID