RGS2
Gene Ontology Biological Process
- negative regulation of G-protein coupled receptor protein signaling pathway [ISS]
- negative regulation of MAP kinase activity [ISS]
- negative regulation of cardiac muscle hypertrophy [ISS]
- negative regulation of phospholipase activity [ISS]
- positive regulation of cardiac muscle contraction [ISS]
- regulation of G-protein coupled receptor protein signaling pathway [TAS]
- regulation of adrenergic receptor signaling pathway [ISS]
- relaxation of cardiac muscle [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GIT1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
RGS2 GIT1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | 4 | BioGRID | - |
Curated By
- BioGRID