BAIT
STK3
KRS1, MST2
serine/threonine kinase 3
GO Process (13)
GO Function (8)
GO Component (2)
Gene Ontology Biological Process
- apoptotic process [TAS]
- hippo signaling [IDA, TAS]
- intracellular signal transduction [IDA]
- negative regulation of canonical Wnt signaling pathway [IMP]
- positive regulation of apoptotic process [ISS]
- positive regulation of fat cell differentiation [IGI]
- positive regulation of protein binding [IDA]
- positive regulation of protein serine/threonine kinase activity [TAS]
- positive regulation of sequence-specific DNA binding transcription factor activity [IGI]
- protein phosphorylation [IDA]
- protein stabilization [IMP]
- signal transduction [TAS]
- signal transduction by phosphorylation [IBA]
Gene Ontology Molecular Function- ATP binding [IDA]
- magnesium ion binding [IDA]
- protein binding [IPI]
- protein dimerization activity [ISS]
- protein kinase activity [TAS]
- protein serine/threonine kinase activator activity [TAS]
- protein serine/threonine kinase activity [EXP, IDA]
- receptor signaling protein serine/threonine kinase activity [IBA]
- ATP binding [IDA]
- magnesium ion binding [IDA]
- protein binding [IPI]
- protein dimerization activity [ISS]
- protein kinase activity [TAS]
- protein serine/threonine kinase activator activity [TAS]
- protein serine/threonine kinase activity [EXP, IDA]
- receptor signaling protein serine/threonine kinase activity [IBA]
Homo sapiens
PREY
MPP1
AAG12, DXS552E, EMP55, MRG1, PEMP
membrane protein, palmitoylated 1, 55kDa
GO Process (3)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID