BAIT
SRGN
PPG, PRG, PRG1
serglycin
GO Process (11)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
- T cell secretory granule organization [ISS]
- blood coagulation [TAS]
- granzyme-mediated apoptotic signaling pathway [IDA]
- maintenance of granzyme B location in T cell secretory granule [ISS]
- maintenance of protease location in mast cell secretory granule [ISS]
- mast cell secretory granule organization [ISS]
- negative regulation of bone mineralization [IDA]
- negative regulation of cytokine secretion [ISS]
- platelet activation [TAS]
- platelet degranulation [TAS]
- protein processing [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PSRC1
DDA3, FP3214, RP11-297O4.2
proline/serine-rich coiled-coil 1
GO Process (7)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
- microtubule bundle formation [ISS]
- mitotic metaphase plate congression [IDA]
- negative regulation of cell growth [ISS]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity [ISS]
- positive regulation of microtubule polymerization [ISS]
- positive regulation of transcription, DNA-templated [ISS]
- regulation of mitotic spindle organization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID