BAIT
ANXA7
ANX7, SNX, SYNEXIN, RP11-537A6.8
annexin A7
GO Process (4)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DVL1
DVL, DVL1L1, DVL1P1, RP5-890O3.5
dishevelled segment polarity protein 1
GO Process (18)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- Wnt signaling pathway, planar cell polarity pathway [IDA]
- canonical Wnt signaling pathway [IDA]
- dendrite morphogenesis [ISS]
- heart development [NAS]
- negative regulation of protein binding [IDA]
- negative regulation of protein kinase activity [IDA]
- neural tube development [IEP]
- neuromuscular junction development [ISS]
- neurotransmitter secretion [ISS]
- planar cell polarity pathway involved in neural tube closure [IBA]
- positive regulation of Wnt signaling pathway [IDA]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- positive regulation of transcription, DNA-templated [IDA]
- protein localization to nucleus [IMP]
- receptor clustering [ISS]
- regulation of neurotransmitter levels [ISS]
- synapse organization [ISS]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID