BAIT
ANXA7
ANX7, SNX, SYNEXIN, RP11-537A6.8
annexin A7
GO Process (4)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
INPP5K
PPS, SKIP
inositol polyphosphate-5-phosphatase K
GO Process (37)
GO Function (8)
GO Component (11)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [ISS]
- actin cytoskeleton organization [NAS]
- cellular response to cAMP [ISS]
- cellular response to epidermal growth factor stimulus [IDA]
- cellular response to hormone stimulus [ISS]
- cellular response to insulin stimulus [IDA]
- cellular response to tumor necrosis factor [IDA]
- dephosphorylation [IDA, IMP]
- glucose homeostasis [ISS]
- inositol phosphate dephosphorylation [IDA]
- negative regulation by host of viral transcription [IDA]
- negative regulation of MAP kinase activity [IDA]
- negative regulation of calcium ion transport [IDA]
- negative regulation of dephosphorylation [ISS]
- negative regulation of glucose transport [IDA]
- negative regulation of glycogen (starch) synthase activity [ISS]
- negative regulation of glycogen biosynthetic process [IDA]
- negative regulation of insulin receptor signaling pathway [IDA]
- negative regulation of peptidyl-serine phosphorylation [IDA]
- negative regulation of peptidyl-threonine phosphorylation [IDA]
- negative regulation of protein kinase B signaling [IDA]
- negative regulation of protein kinase activity [IDA]
- negative regulation of protein phosphorylation [ISS]
- negative regulation of protein targeting to membrane [IDA]
- negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [IDA]
- negative regulation of stress fiber assembly [IDA]
- negative regulation of transcription, DNA-templated [ISS]
- phosphatidylinositol biosynthetic process [TAS]
- phosphatidylinositol dephosphorylation [IDA]
- phospholipid metabolic process [TAS]
- positive regulation of renal water transport [ISS]
- positive regulation of transcription, DNA-templated [ISS]
- positive regulation of urine volume [ISS]
- protein targeting to plasma membrane [ISS]
- regulation of glycogen biosynthetic process [ISS]
- ruffle assembly [IDA]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function- inositol bisphosphate phosphatase activity [IDA]
- inositol trisphosphate phosphatase activity [IDA]
- lipid phosphatase activity [NAS]
- phosphatidylinositol phosphate 5-phosphatase activity [IMP]
- phosphatidylinositol trisphosphate phosphatase activity [IDA]
- phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [IDA]
- protein binding [IPI]
- vasopressin receptor activity [ISS]
- inositol bisphosphate phosphatase activity [IDA]
- inositol trisphosphate phosphatase activity [IDA]
- lipid phosphatase activity [NAS]
- phosphatidylinositol phosphate 5-phosphatase activity [IMP]
- phosphatidylinositol trisphosphate phosphatase activity [IDA]
- phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [IDA]
- protein binding [IPI]
- vasopressin receptor activity [ISS]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID