BAIT
NR4A1
GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3
nuclear receptor subfamily 4, group A, member 1
GO Process (16)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- cell migration involved in sprouting angiogenesis [IDA]
- cellular response to fibroblast growth factor stimulus [IMP]
- cellular response to vascular endothelial growth factor stimulus [IMP]
- endothelial cell chemotaxis [IMP]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- gene expression [TAS]
- innate immune response [TAS]
- intracellular receptor signaling pathway [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- phosphatidylinositol-mediated signaling [TAS]
- positive regulation of endothelial cell proliferation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- signal transduction [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cytoplasm [IDA]
- nuclear membrane [IDA]
- nucleoplasm [IDA, TAS]
- nucleus [IDA, ISS]
Homo sapiens
PREY
PPBP
B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
GO Process (12)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IBA]
- blood coagulation [TAS]
- cell chemotaxis [IBA]
- chemokine-mediated signaling pathway [IBA]
- glucose transport [TAS]
- immune response [IBA]
- inflammatory response [IBA]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of leukocyte chemotaxis [IBA]
- regulation of cell proliferation [IBA]
- response to lipopolysaccharide [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID