BAIT
GADD45A
DDIT1, GADD45, RP5-975D15.1
growth arrest and DNA-damage-inducible, alpha
GO Process (11)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- DNA repair [TAS]
- activation of MAPKKK activity [IDA]
- apoptotic process [TAS]
- cellular response to ionizing radiation [IMP]
- cellular response to mechanical stimulus [IEP]
- positive regulation of JNK cascade [IDA]
- positive regulation of apoptotic process [IDA]
- positive regulation of p38MAPK cascade [IDA]
- positive regulation of reactive oxygen species metabolic process [IMP]
- regulation of cyclin-dependent protein serine/threonine kinase activity [TAS]
- signal transduction in response to DNA damage [IMP]
Gene Ontology Molecular Function
Homo sapiens
PREY
MPP1
AAG12, DXS552E, EMP55, MRG1, PEMP
membrane protein, palmitoylated 1, 55kDa
GO Process (3)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID