BAIT
FRZB
FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, OS1, SFRP3, SRFP3, hFIZ
frizzled-related protein
GO Process (8)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- negative regulation of Wnt signaling pathway [IDA, ISS]
- negative regulation of canonical Wnt signaling pathway [IDA]
- negative regulation of cell growth [IDA]
- negative regulation of cell proliferation [IDA]
- non-canonical Wnt signaling pathway [IBA]
- positive regulation of apoptotic process [IGI]
- positive regulation of fat cell differentiation [IDA]
- skeletal system development [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ELF5
ESE2
E74-like factor 5 (ets domain transcription factor)
GO Process (4)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID