BAIT
IGF2
C11orf43, IGF-II, PP9974, PP1446
insulin-like growth factor 2
GO Process (21)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- blood coagulation [TAS]
- cellular protein metabolic process [TAS]
- insulin receptor signaling pathway [TAS]
- insulin receptor signaling pathway via phosphatidylinositol 3-kinase [ISS]
- multicellular organismal development [TAS]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of MAPK cascade [IDA]
- positive regulation of activated T cell proliferation [IDA]
- positive regulation of catalytic activity [ISS]
- positive regulation of cell proliferation [IC]
- positive regulation of glycogen (starch) synthase activity [ISS]
- positive regulation of glycogen biosynthetic process [ISS]
- positive regulation of insulin receptor signaling pathway [IDA]
- positive regulation of mitosis [IDA]
- positive regulation of peptidyl-tyrosine phosphorylation [ISS]
- positive regulation of protein kinase B signaling [IDA]
- positive regulation of protein phosphorylation [ISS]
- regulation of gene expression by genetic imprinting [TAS]
- regulation of transcription, DNA-templated [NAS]
- skeletal system development [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BAG6
BAG-6, BAT3, D6S52E, G3, DADB-70P7.10-021
BCL2-associated athanogene 6
GO Process (14)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- brain development [ISS]
- embryo development [ISS]
- internal peptidyl-lysine acetylation [IDA]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISS]
- kidney development [ISS]
- lung development [ISS]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- negative regulation of proteolysis [ISS]
- protein stabilization [ISS]
- spermatogenesis [ISS]
- synaptonemal complex assembly [ISS]
- tail-anchored membrane protein insertion into ER membrane [IDA]
- ubiquitin-dependent protein catabolic process [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID