BAIT
MAD
2/23, CG12399, Dmel\CG12399, E(zen)2, En(vvl), Mat, P-Mad, PMad, Smad, Smad1, apg, c28, dMAD, l(2)K00237, pSmad, Dmel_CG12399
Mothers against dpp
GO Process (24)
GO Function (9)
GO Component (2)
Gene Ontology Biological Process
- BMP signaling pathway involved in Malpighian tubule cell chemotaxis [IDA]
- compound eye morphogenesis [IMP]
- dorsal closure [NAS]
- germ-line stem cell division [IMP, TAS]
- germ-line stem cell maintenance [IMP]
- heart development [TAS]
- histoblast morphogenesis [IMP]
- imaginal disc-derived leg morphogenesis [IMP]
- imaginal disc-derived wing morphogenesis [IMP]
- imaginal disc-derived wing vein morphogenesis [IMP]
- negative regulation of G1/S transition of mitotic cell cycle [IMP]
- negative regulation of gene expression [IDA]
- negative regulation of salivary gland boundary specification [TAS]
- open tracheal system development [TAS]
- ovarian follicle cell development [IMP, TAS]
- positive regulation of synaptic growth at neuromuscular junction [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IEP, IMP]
- regulation of cell differentiation [IMP]
- regulation of transcription from RNA polymerase II promoter [NAS]
- somatic stem cell maintenance [IMP]
- transforming growth factor beta receptor signaling pathway [IGI, NAS, TAS]
- transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification [IMP]
- trunk segmentation [IMP]
- wing disc anterior/posterior pattern formation [IMP]
Gene Ontology Molecular Function- DNA binding [TAS]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription coactivator activity [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- transcription regulatory region sequence-specific DNA binding [IDA]
- transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [NAS]
- DNA binding [TAS]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription coactivator activity [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- transcription regulatory region sequence-specific DNA binding [IDA]
- transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [NAS]
Drosophila melanogaster
PREY
BCD
BG:DS00276.7, CG1034, Dmel\CG1034, bic, mum, prd4, Dmel_CG1034
bicoid
GO Process (11)
GO Function (7)
GO Component (1)
Gene Ontology Biological Process
- anterior region determination [IMP]
- anterior/posterior axis specification [TAS]
- anterior/posterior axis specification, embryo [NAS, TAS]
- maternal determination of anterior/posterior axis, embryo [NAS, TAS]
- negative regulation of translation [IGI, IMP, TAS]
- oogenesis [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of transcription from RNA polymerase II promoter [NAS]
- regulation of transcription, DNA-templated [IMP, NAS]
- regulation of translation [TAS]
- segment polarity determination [IMP]
Gene Ontology Molecular Function- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- mRNA 3'-UTR binding [IMP]
- morphogen activity [NAS]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- translation regulator activity [TAS]
- translation repressor activity [IGI]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- mRNA 3'-UTR binding [IMP]
- morphogen activity [NAS]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- translation regulator activity [TAS]
- translation repressor activity [IGI]
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A Drosophila protein-interaction map centered on cell-cycle regulators.
BACKGROUND: Maps depicting binary interactions between proteins can be powerful starting points for understanding biological systems. A proven technology for generating such maps is high-throughput yeast two-hybrid screening. In the most extensive screen to date, a Gal4-based two-hybrid system was used recently to detect over 20,000 interactions among Drosophila proteins. Although these data are a valuable resource for insights into ... [more]
Genome Biol. Dec. 04, 2004; 5(12);R96 [Pubmed: 15575970]
Throughput
- High Throughput
Curated By
- BioGRID