MAD
Gene Ontology Biological Process
- BMP signaling pathway involved in Malpighian tubule cell chemotaxis [IDA]
- compound eye morphogenesis [IMP]
- dorsal closure [NAS]
- germ-line stem cell division [IMP, TAS]
- germ-line stem cell maintenance [IMP]
- heart development [TAS]
- histoblast morphogenesis [IMP]
- imaginal disc-derived leg morphogenesis [IMP]
- imaginal disc-derived wing morphogenesis [IMP]
- imaginal disc-derived wing vein morphogenesis [IMP]
- negative regulation of G1/S transition of mitotic cell cycle [IMP]
- negative regulation of gene expression [IDA]
- negative regulation of salivary gland boundary specification [TAS]
- open tracheal system development [TAS]
- ovarian follicle cell development [IMP, TAS]
- positive regulation of synaptic growth at neuromuscular junction [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IEP, IMP]
- regulation of cell differentiation [IMP]
- regulation of transcription from RNA polymerase II promoter [NAS]
- somatic stem cell maintenance [IMP]
- transforming growth factor beta receptor signaling pathway [IGI, NAS, TAS]
- transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification [IMP]
- trunk segmentation [IMP]
- wing disc anterior/posterior pattern formation [IMP]
Gene Ontology Molecular Function- DNA binding [TAS]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription coactivator activity [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- transcription regulatory region sequence-specific DNA binding [IDA]
- transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [NAS]
- DNA binding [TAS]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription coactivator activity [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- transcription regulatory region sequence-specific DNA binding [IDA]
- transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [NAS]
CG8993
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A Drosophila protein-interaction map centered on cell-cycle regulators.
BACKGROUND: Maps depicting binary interactions between proteins can be powerful starting points for understanding biological systems. A proven technology for generating such maps is high-throughput yeast two-hybrid screening. In the most extensive screen to date, a Gal4-based two-hybrid system was used recently to detect over 20,000 interactions among Drosophila proteins. Although these data are a valuable resource for insights into ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
MAD CG8993 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID