BAIT

CYC1

cytochrome c isoform 1, L000000448, YJR048W
Cytochrome c, isoform 1; also known as iso-1-cytochrome c; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration; mutations in human homolog cause insulin-responsive hyperglycemia; CYC1 has a paralog, CYC7, that arose from the whole genome duplication
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)
PREY

SUP3

L000003705, L000002182, tY(GUA)O
Tyrosine tRNA (tRNA-Tyr), predicted by tRNAscan-SE analysis; can mutate to suppress ochre nonsense mutations
GO Process (1)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)

Dosage Rescue

A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene.

Publication

Amino acid replacements resulting from super-suppression of nonsense mutants of iso-1-cytochrome c from yeast.

Gilmore RA, Stewart JW, Sherman F

... [more]

J. Mol. Biol. Oct. 14, 1971; 61(1);157-73 [Pubmed: 5146189]

Throughput

  • Low Throughput

Ontology Terms

  • phenotype: vegetative growth (APO:0000106)
  • phenotype: utilization of carbon source (APO:0000098)

Additional Notes

  • Suppression of the cy1 mutation allows growth on lactate

Curated By

  • BioGRID