CEBPG
Gene Ontology Biological Process
- B cell differentiation [ISS]
- enucleate erythrocyte differentiation [ISO, ISS]
- immune response [ISO, ISS]
- liver development [IEP]
- mRNA metabolic process [ISO]
- natural killer cell mediated cytotoxicity [ISO, ISS]
- negative regulation of sequence-specific DNA binding transcription factor activity [ISO, ISS]
- positive regulation of DNA repair [ISO, ISS]
- positive regulation of interferon-gamma biosynthetic process [ISO, ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- regulation of transcription from RNA polymerase II promoter [IEP, ISO]
- regulation of transcription, DNA-templated [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- double-stranded DNA binding [IDA]
- protein binding [IPI]
- protein heterodimerization activity [IDA, ISO]
- sequence-specific DNA binding [ISO, ISS]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [ISO, ISS]
- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- double-stranded DNA binding [IDA]
- protein binding [IPI]
- protein heterodimerization activity [IDA, ISO]
- sequence-specific DNA binding [ISO, ISS]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [ISO, ISS]
Gene Ontology Cellular Component
- nucleoplasm [ISO]
- nucleus [ISO, ISS]
SMARCD2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Aging reduces proliferative capacities of liver by switching pathways of C/EBPalpha growth arrest.
The liver is capable of completely regenerating itself in response to injury and after partial hepatectomy. In liver of old animals, the proliferative response is dramatically reduced, the mechanism for which is unknown. The liver specific protein, C/EBPalpha, normally arrests proliferation of hepatocytes through inhibiting cyclin dependent kinases (cdks). We present evidence that aging switches the liver-specific pathway of C/EBPalpha ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CEBPG SMARCD2 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | Low | - | BioGRID | - |
Curated By
- BioGRID