BAIT

SHFM1

DSS1, ECD, SEM1, SHFD1, SHSF1, Shfdg1
split hand/foot malformation (ectrodactyly) type 1
GO Process (1)
GO Function (1)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

SAC3D1

HSU79266, SHD1
SAC3 domain containing 1
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

Baillat D, Hakimi MA, Naeaer AM, Shilatifard A, Cooch N, Shiekhattar R

The C-terminal domain (CTD) of RNA polymerase II (RNAPII) is an essential component of transcriptional regulation and RNA processing of protein-coding genes. A large body of data also implicates the CTD in the transcription and processing of RNAPII-mediated small nuclear RNAs (snRNAs). However, the identity of the complex (or complexes) that associates with the CTD and mediates the processing of ... [more]

Cell Oct. 21, 2005; 123(2);265-76 [Pubmed: 16239144]

Throughput

  • Low Throughput

Curated By

  • BioGRID