BAIT
GRM8
Glur8, Gprc1h, Mglur8, mGluR8b, mGlur
glutamate receptor, metabotropic 8
GO Process (9)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway [IBA, ISO, ISS, TAS]
- detection of mechanical stimulus involved in sensory perception of pain [IDA]
- negative regulation of cAMP biosynthetic process [ISO]
- regulation of neuron death [TAS]
- regulation of neurotransmitter secretion [IDA]
- regulation of synaptic transmission, glutamatergic [IBA]
- sensory perception of pain [TAS]
- synaptic transmission [IDA, NAS]
- synaptic transmission, glutamatergic [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PIAS3
ZMIZ5
protein inhibitor of activated STAT, 3
GO Process (2)
GO Function (3)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
SUMO E3 ligases are expressed in the retina and regulate SUMOylation of the metabotropic glutamate receptor 8b.
The central nervous system regulates neuronal excitability by macromolecular signalling complexes that consist of functionally related proteins, including neurotransmitter receptors, enzymes and scaffolds. The composition of these signal complexes is regulated by post-translational modifications, such as phosphorylation and SUMOylation (SUMO is small ubiquitin-related modifier). In the present study, we searched for proteins interacting with the intracellular C-termini of the metabotropic ... [more]
Biochem. J. Apr. 15, 2011; 435(2);365-71 [Pubmed: 21288202]
Throughput
- Low Throughput
Curated By
- BioGRID