BAIT
SUMO3
small ubiquitin-like modifier 3
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
UBE2I
UbcE2A
ubiquitin-conjugating enzyme E2I
GO Process (10)
GO Function (12)
GO Component (8)
Gene Ontology Biological Process
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of intracellular steroid hormone receptor signaling pathway [IDA]
- positive regulation of sequence-specific DNA binding transcription factor activity [IDA]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IMP]
- protein sumoylation [IDA, ISO]
- protein ubiquitination [IDA]
- regulation of receptor activity [IDA]
- ubiquitin-dependent protein catabolic process [TAS]
Gene Ontology Molecular Function- HLH domain binding [ISO]
- RING-like zinc finger domain binding [ISO]
- SUMO transferase activity [IDA, ISO]
- bHLH transcription factor binding [IPI]
- enzyme binding [ISO]
- poly(A) RNA binding [ISO]
- protein C-terminus binding [IPI]
- protein binding [IPI]
- transcription factor binding [ISO]
- ubiquitin protein ligase activity [IBA]
- ubiquitin protein ligase binding [IBA]
- ubiquitin-protein transferase activity [IDA]
- HLH domain binding [ISO]
- RING-like zinc finger domain binding [ISO]
- SUMO transferase activity [IDA, ISO]
- bHLH transcription factor binding [IPI]
- enzyme binding [ISO]
- poly(A) RNA binding [ISO]
- protein C-terminus binding [IPI]
- protein binding [IPI]
- transcription factor binding [ISO]
- ubiquitin protein ligase activity [IBA]
- ubiquitin protein ligase binding [IBA]
- ubiquitin-protein transferase activity [IDA]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Analysis of Oxygen/Glucose-Deprivation-Induced Changes in SUMO3 Conjugation Using SILAC-Based Quantitative Proteomics.
Transient cerebral ischemia dramatically activates small ubiquitin-like modifier (SUMO2/3) conjugation. In cells exposed to 6 h of transient oxygen/glucose deprivation (OGD), a model of ischemia, SUMOylation increases profoundly between 0 and 30 min following re-oxygenation. To elucidate the effect of transient OGD on SUMO conjugation of target proteins, we exposed neuroblastoma B35 cells expressing HA-SUMO3 to transient OGD and used ... [more]
J. Proteome Res. Dec. 01, 2011; 0(0); [Pubmed: 22082260]
Throughput
- High Throughput
Curated By
- BioGRID