BAIT
SUMO3
small ubiquitin-like modifier 3
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PPP2CA
Pp2a1
protein phosphatase 2, catalytic subunit, alpha isozyme
GO Process (26)
GO Function (16)
GO Component (9)
Gene Ontology Biological Process
- cardiac ventricle development [IEP]
- cellular response to calcium ion [IEP]
- cellular response to cytokine stimulus [IEP]
- cellular response to ethanol [IEP]
- cellular response to follicle-stimulating hormone stimulus [IEP]
- cellular response to glucose stimulus [IEP, IMP]
- cellular response to insulin stimulus [IEP]
- cellular response to steroid hormone stimulus [IEP]
- heart development [IEP]
- mesoderm development [ISO]
- negative regulation of calcium ion transmembrane transporter activity [IMP]
- negative regulation of epithelial to mesenchymal transition [ISO]
- negative regulation of protein phosphorylation [IMP]
- negative regulation of transcription factor import into nucleus [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of apoptotic process [IMP]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- positive regulation of protein dephosphorylation [IDA]
- positive regulation of protein phosphatase type 2A activity [IMP]
- positive regulation of protein serine/threonine kinase activity [ISO]
- protein dephosphorylation [IDA]
- protein heterotrimerization [IMP]
- regulation of protein autophosphorylation [IMP]
- regulation of protein catabolic process [IMP]
- regulation of protein phosphorylation [IMP]
- regulation of receptor activity [IMP]
Gene Ontology Molecular Function- GABA receptor binding [ISO]
- enzyme binding [IPI]
- ion channel binding [IPI]
- protein C-terminus binding [IPI, ISO]
- protein antigen binding [IPI]
- protein binding [IPI]
- protein complex binding [IPI]
- protein dimerization activity [IMP]
- protein domain specific binding [IDA]
- protein heterodimerization activity [ISS]
- protein kinase B binding [IPI]
- protein kinase binding [IDA]
- protein phosphatase 2A binding [IDA, IPI]
- protein phosphatase binding [IPI]
- protein serine/threonine phosphatase activity [IDA, IMP, TAS]
- tau protein binding [IPI]
- GABA receptor binding [ISO]
- enzyme binding [IPI]
- ion channel binding [IPI]
- protein C-terminus binding [IPI, ISO]
- protein antigen binding [IPI]
- protein binding [IPI]
- protein complex binding [IPI]
- protein dimerization activity [IMP]
- protein domain specific binding [IDA]
- protein heterodimerization activity [ISS]
- protein kinase B binding [IPI]
- protein kinase binding [IDA]
- protein phosphatase 2A binding [IDA, IPI]
- protein phosphatase binding [IPI]
- protein serine/threonine phosphatase activity [IDA, IMP, TAS]
- tau protein binding [IPI]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Analysis of Oxygen/Glucose-Deprivation-Induced Changes in SUMO3 Conjugation Using SILAC-Based Quantitative Proteomics.
Transient cerebral ischemia dramatically activates small ubiquitin-like modifier (SUMO2/3) conjugation. In cells exposed to 6 h of transient oxygen/glucose deprivation (OGD), a model of ischemia, SUMOylation increases profoundly between 0 and 30 min following re-oxygenation. To elucidate the effect of transient OGD on SUMO conjugation of target proteins, we exposed neuroblastoma B35 cells expressing HA-SUMO3 to transient OGD and used ... [more]
J. Proteome Res. Dec. 01, 2011; 0(0); [Pubmed: 22082260]
Throughput
- High Throughput
Curated By
- BioGRID