BAIT

SUMO3

small ubiquitin-like modifier 3

GO Process (3)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISO]

protein localization to nucleus [ISO]

protein sumoylation [ISO]

Gene Ontology Molecular Function

SUMO transferase activity [ISO]

Gene Ontology Cellular Component

extracellular vesicular exosome [ISO]

nuclear body [ISO]

RGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Rattus norvegicus

PREY

CLTC

clathrin, heavy chain (Hc)

GO Process (8)

GO Function (8)

GO Component (18)

Gene Ontology Biological Process

Golgi organization [IMP]

mitotic nuclear division [IMP, ISO]

negative regulation of hyaluronan biosynthetic process [ISO, ISS]

negative regulation of protein localization to plasma membrane [ISO]

osteoblast differentiation [ISO]

receptor internalization [ISO]

receptor-mediated endocytosis [IMP, ISO]

transferrin transport [ISO]

Gene Ontology Molecular Function

ankyrin binding [IDA]
clathrin light chain binding [ISO]
double-stranded RNA binding [ISO]
heat shock protein binding [IDA]
peptide binding [IDA]
poly(A) RNA binding [ISO]
protein C-terminus binding [IPI]
protein binding [IPI]

Gene Ontology Cellular Component

clathrin coat [IDA, TAS]

clathrin complex [ISO]

clathrin-coated endocytic vesicle membrane [TAS]

clathrin-coated vesicle [ISO]

cytoplasm [ISO]

extracellular vesicular exosome [ISO]

focal adhesion [ISO]

intracellular membrane-bounded organelle [ISO]

membrane coat [ISO]

mitochondrion [ISO]

myelin sheath [ISO]

protein complex [ISO]

sarcolemma [IDA]

spindle [IDA, ISO]

terminal bouton [IDA]

RGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Rattus norvegicus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Analysis of Oxygen/Glucose-Deprivation-Induced Changes in SUMO3 Conjugation Using SILAC-Based Quantitative Proteomics.

Yang W, Thompson JW, Wang Z, Wang L, Sheng H, Foster MW, Moseley MA, Paschen W

Transient cerebral ischemia dramatically activates small ubiquitin-like modifier (SUMO2/3) conjugation. In cells exposed to 6 h of transient oxygen/glucose deprivation (OGD), a model of ischemia, SUMOylation increases profoundly between 0 and 30 min following re-oxygenation. To elucidate the effect of transient OGD on SUMO conjugation of target proteins, we exposed neuroblastoma B35 cells expressing HA-SUMO3 to transient OGD and used ... [more]

J. Proteome Res. Dec. 01, 2011; 0(0); [Pubmed: 22082260]

Throughput

High Throughput

Curated By

BioGRID