BAIT
SUMO3
small ubiquitin-like modifier 3
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
SOX10
SRY (sex determining region Y)-box 10
GO Process (21)
GO Function (12)
GO Component (3)
Gene Ontology Biological Process
- cell development [NAS]
- cell differentiation [ISO]
- cell maturation [ISO]
- developmental growth [ISO]
- digestive tract morphogenesis [ISO]
- enteric nervous system development [ISO]
- in utero embryonic development [ISO]
- melanocyte differentiation [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of canonical Wnt signaling pathway [ISO]
- negative regulation of transcription, DNA-templated [IDA]
- neural crest cell migration [ISO]
- oligodendrocyte differentiation [ISO]
- peripheral nervous system development [ISO]
- positive regulation of gliogenesis [ISO]
- positive regulation of neuroblast proliferation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [IDA, ISO]
- regulation of transcription, DNA-templated [IDA]
- stem cell differentiation [IEP]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [ISO]
- chromatin binding [ISO]
- identical protein binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [IDA, IPI]
- transcription regulatory region DNA binding [ISO]
- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [ISO]
- chromatin binding [ISO]
- identical protein binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [IDA, IPI]
- transcription regulatory region DNA binding [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Analysis of Oxygen/Glucose-Deprivation-Induced Changes in SUMO3 Conjugation Using SILAC-Based Quantitative Proteomics.
Transient cerebral ischemia dramatically activates small ubiquitin-like modifier (SUMO2/3) conjugation. In cells exposed to 6 h of transient oxygen/glucose deprivation (OGD), a model of ischemia, SUMOylation increases profoundly between 0 and 30 min following re-oxygenation. To elucidate the effect of transient OGD on SUMO conjugation of target proteins, we exposed neuroblastoma B35 cells expressing HA-SUMO3 to transient OGD and used ... [more]
J. Proteome Res. Dec. 01, 2011; 0(0); [Pubmed: 22082260]
Throughput
- High Throughput
Curated By
- BioGRID