BAIT
SUMO3
small ubiquitin-like modifier 3
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
NEFL
NF-L, Nfl
neurofilament, light polypeptide
GO Process (21)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- anterograde axon cargo transport [ISO]
- axon transport of mitochondrion [ISO]
- intermediate filament bundle assembly [ISO]
- intermediate filament organization [ISO]
- locomotion [ISO]
- microtubule cytoskeleton organization [ISO]
- negative regulation of neuron apoptotic process [ISO]
- neurofilament bundle assembly [ISO]
- neurofilament cytoskeleton organization [ISO]
- neuromuscular process controlling balance [ISO]
- neuron projection morphogenesis [ISO]
- peripheral nervous system axon regeneration [ISO]
- positive regulation of axonogenesis [ISO]
- protein polymerization [IDA]
- regulation of axon diameter [ISO]
- response to corticosterone [IEP]
- response to organic substance [IEP]
- response to organonitrogen compound [IEP]
- response to peptide hormone [IEP]
- response to toxic substance [IEP]
- retrograde axon cargo transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Analysis of Oxygen/Glucose-Deprivation-Induced Changes in SUMO3 Conjugation Using SILAC-Based Quantitative Proteomics.
Transient cerebral ischemia dramatically activates small ubiquitin-like modifier (SUMO2/3) conjugation. In cells exposed to 6 h of transient oxygen/glucose deprivation (OGD), a model of ischemia, SUMOylation increases profoundly between 0 and 30 min following re-oxygenation. To elucidate the effect of transient OGD on SUMO conjugation of target proteins, we exposed neuroblastoma B35 cells expressing HA-SUMO3 to transient OGD and used ... [more]
J. Proteome Res. Dec. 01, 2011; 0(0); [Pubmed: 22082260]
Throughput
- High Throughput
Curated By
- BioGRID