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BAIT

SUMO3

small ubiquitin-like modifier 3

GO Process (3)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISO]

protein localization to nucleus [ISO]

protein sumoylation [ISO]

Gene Ontology Molecular Function

SUMO transferase activity [ISO]

Gene Ontology Cellular Component

extracellular vesicular exosome [ISO]

nuclear body [ISO]

RGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Rattus norvegicus

PREY

ACTN4

actinin alpha 4

GO Process (8)

GO Function (6)

GO Component (15)

Gene Ontology Biological Process

actin filament bundle assembly [ISO]

negative regulation of cellular component movement [ISO]

positive regulation of cellular component movement [ISO]

positive regulation of pinocytosis [ISO]

protein localization to tight junction [ISO]

regulation of apoptotic process [IMP]

response to hypoxia [IEP]

tight junction assembly [ISO]

Gene Ontology Molecular Function

actin filament binding [ISO]
nucleoside binding [ISO]
poly(A) RNA binding [ISO]
protein N-terminus binding [IPI]
protein binding [IPI]
protein complex binding [IPI]

Gene Ontology Cellular Component

cell-cell junction [ISO]

cortical cytoskeleton [ISO]

cytoplasm [IDA, ISO]

extracellular space [ISO]

extracellular vesicular exosome [ISO]

focal adhesion [ISO]

neuron projection [IDA]

nucleus [IDA, ISO]

perinuclear region of cytoplasm [ISO]

protein complex [IDA, ISO]

pseudopodium [ISO]

ribonucleoprotein complex [ISO, ISS]

stress fiber [IDA, ISO]

RGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Rattus norvegicus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Analysis of Oxygen/Glucose-Deprivation-Induced Changes in SUMO3 Conjugation Using SILAC-Based Quantitative Proteomics.

Yang W, Thompson JW, Wang Z, Wang L, Sheng H, Foster MW, Moseley MA, Paschen W

Transient cerebral ischemia dramatically activates small ubiquitin-like modifier (SUMO2/3) conjugation. In cells exposed to 6 h of transient oxygen/glucose deprivation (OGD), a model of ischemia, SUMOylation increases profoundly between 0 and 30 min following re-oxygenation. To elucidate the effect of transient OGD on SUMO conjugation of target proteins, we exposed neuroblastoma B35 cells expressing HA-SUMO3 to transient OGD and used ... [more]

J. Proteome Res. Dec. 01, 2011; 0(0); [Pubmed: 22082260]

Throughput

High Throughput

Curated By

BioGRID