SUMO3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RUNX1
Gene Ontology Biological Process
- behavioral response to pain [ISO]
- cellular response to transforming growth factor beta stimulus [ISO]
- central nervous system development [ISO]
- definitive hemopoiesis [ISO]
- embryonic hemopoiesis [ISO]
- hair follicle morphogenesis [ISO]
- hemopoiesis [ISO]
- in utero embryonic development [ISO]
- liver development [ISO]
- myeloid cell differentiation [ISO]
- myeloid progenitor cell differentiation [ISO]
- negative regulation of granulocyte differentiation [ISO]
- neuron development [ISO]
- neuron differentiation [ISO]
- positive regulation of angiogenesis [ISO, ISS]
- positive regulation of granulocyte differentiation [ISO, ISS]
- positive regulation of progesterone secretion [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of hair follicle cell proliferation [ISO]
- regulation of signal transduction [ISO]
- regulation of transcription, DNA-templated [ISO, TAS]
- response to retinoic acid [ISO]
- skeletal system development [ISO]
Gene Ontology Molecular Function- DNA binding [ISO]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- calcium ion binding [ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- regulatory region DNA binding [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [ISO]
- DNA binding [ISO]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- calcium ion binding [ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- regulatory region DNA binding [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [ISO]
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Analysis of Oxygen/Glucose-Deprivation-Induced Changes in SUMO3 Conjugation Using SILAC-Based Quantitative Proteomics.
Transient cerebral ischemia dramatically activates small ubiquitin-like modifier (SUMO2/3) conjugation. In cells exposed to 6 h of transient oxygen/glucose deprivation (OGD), a model of ischemia, SUMOylation increases profoundly between 0 and 30 min following re-oxygenation. To elucidate the effect of transient OGD on SUMO conjugation of target proteins, we exposed neuroblastoma B35 cells expressing HA-SUMO3 to transient OGD and used ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SUMO3 RUNX1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low/High | - | BioGRID | - |
Curated By
- BioGRID