SUMO3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TRIM28
Gene Ontology Biological Process
- DNA methylation involved in embryo development [ISO]
- DNA repair [ISO]
- convergent extension involved in axis elongation [ISO]
- embryo implantation [ISO]
- embryonic placenta morphogenesis [ISO]
- epithelial to mesenchymal transition [ISO, ISS]
- in utero embryonic development [ISO]
- innate immune response [ISO]
- negative regulation of DNA demethylation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- negative regulation of viral release from host cell [ISO]
- positive regulation of DNA repair [ISO]
- positive regulation of transcription factor import into nucleus [ISO, ISS]
- positive regulation of transcription, DNA-templated [ISO, ISS]
- protein autophosphorylation [ISO]
- protein oligomerization [ISO]
- protein phosphorylation [ISO]
- protein sumoylation [ISO]
- protein ubiquitination [ISO]
- regulation of genetic imprinting [ISO]
Gene Ontology Molecular Function- DNA binding [ISO]
- Krueppel-associated box domain binding [ISO, ISS]
- chromo shadow domain binding [ISO]
- poly(A) RNA binding [ISO]
- protein kinase activity [ISO]
- sequence-specific DNA binding [ISO, ISS]
- sequence-specific DNA binding transcription factor activity [ISO, ISS]
- transcription coactivator activity [ISO]
- transcription corepressor activity [ISO]
- ubiquitin protein ligase binding [ISO]
- ubiquitin-protein transferase activity [ISO]
- zinc ion binding [ISO]
- DNA binding [ISO]
- Krueppel-associated box domain binding [ISO, ISS]
- chromo shadow domain binding [ISO]
- poly(A) RNA binding [ISO]
- protein kinase activity [ISO]
- sequence-specific DNA binding [ISO, ISS]
- sequence-specific DNA binding transcription factor activity [ISO, ISS]
- transcription coactivator activity [ISO]
- transcription corepressor activity [ISO]
- ubiquitin protein ligase binding [ISO]
- ubiquitin-protein transferase activity [ISO]
- zinc ion binding [ISO]
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Analysis of Oxygen/Glucose-Deprivation-Induced Changes in SUMO3 Conjugation Using SILAC-Based Quantitative Proteomics.
Transient cerebral ischemia dramatically activates small ubiquitin-like modifier (SUMO2/3) conjugation. In cells exposed to 6 h of transient oxygen/glucose deprivation (OGD), a model of ischemia, SUMOylation increases profoundly between 0 and 30 min following re-oxygenation. To elucidate the effect of transient OGD on SUMO conjugation of target proteins, we exposed neuroblastoma B35 cells expressing HA-SUMO3 to transient OGD and used ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SUMO3 TRIM28 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low/High | - | BioGRID | - |
Curated By
- BioGRID