BCL10
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- T cell receptor signaling pathway [IDA, TAS]
- adaptive immune response [TAS]
- cell death [IDA]
- cellular response to mechanical stimulus [IEP]
- innate immune response [IEP, TAS]
- interleukin-6 biosynthetic process [NAS]
- lymphotoxin A biosynthetic process [NAS]
- negative regulation of mature B cell apoptotic process [IDA]
- neural tube closure [ISS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IEP]
- positive regulation of NF-kappaB transcription factor activity [IDA]
- positive regulation of extrinsic apoptotic signaling pathway [IDA]
- positive regulation of interleukin-8 biosynthetic process [IMP]
- positive regulation of mast cell cytokine production [NAS]
- positive regulation of phosphorylation [IDA]
- positive regulation of protein ubiquitination [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- protein homooligomerization [ISS, TAS]
- protein oligomerization [IPI]
- response to food [IDA]
- response to molecule of bacterial origin [IEP]
- toll-like receptor signaling pathway [IC]
Gene Ontology Molecular Function- NF-kappaB binding [IDA]
- enzyme binding [IPI]
- kinase activator activity [IDA]
- kinase binding [IPI]
- protease binding [IPI]
- protein C-terminus binding [IPI]
- protein binding [IPI]
- protein kinase B binding [IPI]
- protein kinase binding [IDA]
- protein self-association [IPI]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- ubiquitin binding [IDA]
- ubiquitin protein ligase binding [IPI]
- NF-kappaB binding [IDA]
- enzyme binding [IPI]
- kinase activator activity [IDA]
- kinase binding [IPI]
- protease binding [IPI]
- protein C-terminus binding [IPI]
- protein binding [IPI]
- protein kinase B binding [IPI]
- protein kinase binding [IDA]
- protein self-association [IPI]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- ubiquitin binding [IDA]
- ubiquitin protein ligase binding [IPI]
Gene Ontology Cellular Component
CAMK2G
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
CaMKII targets Bcl10 in T-cell receptor induced activation of NF-κB.
Recognition of antigen by T- or B-cell receptors leads to formation of an immunological synapse and initiation of signalling events that collaborate to determine the nature of the adaptive immune response. Activation of NF-κB transcription factors has a key role in regulation of numerous genes with important functions in immune responses and inflammation and is of great importance for lymphocyte ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID