BAIT

SREK1

SFRS12, SRrp508, SRrp86
splicing regulatory glutamine/lysine-rich protein 1
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

ELAVL1

ELAV1, HUR, Hua, MelG
ELAV like RNA binding protein 1
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Regulation of alternative splicing by SRrp86 and its interacting proteins.

Li J, Hawkins IC, Harvey CD, Jennings JL, Link AJ, Patton JG

SRrp86 is a unique member of the SR protein superfamily containing one RNA recognition motif and two serine-arginine (SR)-rich domains separated by an unusual glutamic acid-lysine (EK)-rich region. Previously, we showed that SRrp86 could regulate alternative splicing by both positively and negatively modulating the activity of other SR proteins and that the unique EK domain could inhibit both constitutive and ... [more]

Mol. Cell. Biol. Nov. 01, 2003; 23(21);7437-47 [Pubmed: 14559993]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
ELAVL1 SREK1
Affinity Capture-RNA
Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

High-BioGRID
664297

Curated By

  • BioGRID