BAIT
PDLIM2
PDZ and LIM domain 2
GO Process (0)
GO Function (5)
GO Component (5)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
MYH9
myosin, heavy chain 9, non-muscle
GO Process (14)
GO Function (9)
GO Component (15)
Gene Ontology Biological Process
- ATP catabolic process [ISS]
- actin cytoskeleton reorganization [ISS]
- actin filament-based movement [ISS]
- angiogenesis [ISS]
- blood vessel endothelial cell migration [ISS]
- membrane protein ectodomain proteolysis [ISS]
- monocyte differentiation [ISS]
- platelet formation [ISS]
- positive regulation of calcium ion transport into cytosol [IMP]
- positive regulation of endocytosis [IMP]
- positive regulation of phagocytosis [IMP]
- protein transport [ISS]
- regulation of cell shape [ISS]
- sodium ion transmembrane transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [ISS]
- actomyosin contractile ring [ISS]
- cell leading edge [ISS]
- cleavage furrow [ISS]
- cytoplasm [IDA, ISS]
- cytosol [ISS]
- endosome [IDA]
- integrin complex [ISS]
- lateral plasma membrane [IDA]
- nucleus [ISS]
- phagocytic vesicle [IDA]
- plasma membrane [ISS]
- protein complex [IDA, ISS]
- ruffle [ISS]
- stress fiber [ISS]
Rattus norvegicus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A.
To characterize properties of Pdlim2, a novel PDZ and LIM domain-containing protein.cDNA encoding Pdlim2 was identified in a cDNA library of transcripts expressed in the tissues of the rat eye irido-corneal angle. The expression pattern of the Pdlim2 gene was studied by Northern blot analysis and in situ hybridization. Proteins interacting with Pdlim2 were identified by pull-down assay and mass ... [more]
Invest. Ophthalmol. Vis. Sci. Nov. 01, 2004; 45(11);3955-63 [Pubmed: 15505042]
Throughput
- Low Throughput
Additional Notes
- pulldown followed by MS for identification
Curated By
- BioGRID