PRKCB
Gene Ontology Biological Process
- B cell activation [ISO, ISS]
- B cell receptor signaling pathway [ISO, ISS]
- calcium ion transport [ISO]
- cellular calcium ion homeostasis [ISO]
- cellular response to carbohydrate stimulus [ISO]
- dibenzo-p-dioxin metabolic process [IEP]
- histone H3-T6 phosphorylation [ISO, ISS]
- intracellular signal transduction [NAS]
- negative regulation of glucose transport [ISO, ISS]
- negative regulation of insulin receptor signaling pathway [IDA]
- positive regulation of B cell receptor signaling pathway [ISO, ISS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO, ISS]
- positive regulation of NF-kappaB transcription factor activity [ISO, ISS]
- positive regulation of angiogenesis [ISO, ISS]
- positive regulation of odontogenesis of dentin-containing tooth [IEP]
- positive regulation of vascular endothelial growth factor receptor signaling pathway [ISO, ISS]
- protein phosphorylation [ISO]
- regulation of dopamine secretion [IMP]
- regulation of growth [IMP]
- regulation of transcription from RNA polymerase II promoter [ISO, ISS]
- response to drug [IMP]
- response to ethanol [IEP]
- response to glucose [IEP]
- response to hypoxia [ISO]
- response to vitamin D [IEP]
Gene Ontology Molecular Function- androgen receptor binding [ISO, ISS]
- calcium channel regulator activity [ISO]
- chromatin binding [ISO, ISS]
- histone binding [ISO, ISS]
- histone kinase activity (H3-T6 specific) [ISO, ISS]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO, ISS]
- protein binding [IPI]
- protein kinase C activity [IDA, ISO]
- protein kinase C binding [ISO]
- protein serine/threonine kinase activity [ISO]
- androgen receptor binding [ISO, ISS]
- calcium channel regulator activity [ISO]
- chromatin binding [ISO, ISS]
- histone binding [ISO, ISS]
- histone kinase activity (H3-T6 specific) [ISO, ISS]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO, ISS]
- protein binding [IPI]
- protein kinase C activity [IDA, ISO]
- protein kinase C binding [ISO]
- protein serine/threonine kinase activity [ISO]
Gene Ontology Cellular Component
RBCK1
Gene Ontology Biological Process
- T cell receptor signaling pathway [ISO]
- negative regulation of NF-kappaB transcription factor activity [ISO]
- negative regulation of necroptotic process [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO, ISS]
- positive regulation of NF-kappaB import into nucleus [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of extrinsic apoptotic signaling pathway [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISO]
- protein linear polyubiquitination [ISO, ISS]
- protein polyubiquitination [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- LUBAC complex [ISO, ISS]
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Molecular cloning and characterization of a novel protein kinase C-interacting protein with structural motifs related to RBCC family proteins.
A novel protein kinase C (PKC)-interacting protein was identified by the yeast two-hybrid screening using the regulatory domain of PKC beta I as a bait. The protein contained several structural motifs such as two putative coiled-coil regions, a RING-finger, a B-box, and a B-box-like motif in the order from NH2- to COOH-terminals. The molecular organization of the protein resembles the ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RBCK1 PRKCB | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID