BAIT
PSMA2
Lmpc3
proteasome (prosome, macropain) subunit, alpha type 2
GO Process (0)
GO Function (0)
GO Component (5)
Gene Ontology Cellular Component
Mus musculus
PREY
TUBA1A
B-ALPHA-1, LIS3, TUBA3
tubulin, alpha 1a
GO Process (8)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37.
The 26S proteasome catalyzes the degradation of most proteins in mammalian cells. To better define its composition and associated regulatory proteins, we developed affinity methods to rapidly purify 26S proteasomes from mammalian cells. By this approach, we discovered a novel 46-kDa (407 residues) subunit of its 19S regulatory complex (previously termed ADRM1 or GP110). As its N-terminal half can be ... [more]
EMBO J. Dec. 13, 2006; 25(24);5742-53 [Pubmed: 17139257]
Throughput
- Low Throughput
Curated By
- BioGRID