BAIT
CYCD
CDI3, CG9096, Cyc D, DmcycD, Dmel\CG9096, cyclinD, dCycD, Dmel_CG9096
Cyclin D
GO Process (6)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Drosophila melanogaster
PREY
BCD
BG:DS00276.7, CG1034, Dmel\CG1034, bic, mum, prd4, Dmel_CG1034
bicoid
GO Process (11)
GO Function (7)
GO Component (1)
Gene Ontology Biological Process
- anterior region determination [IMP]
- anterior/posterior axis specification [TAS]
- anterior/posterior axis specification, embryo [NAS, TAS]
- maternal determination of anterior/posterior axis, embryo [NAS, TAS]
- negative regulation of translation [IGI, IMP, TAS]
- oogenesis [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of transcription from RNA polymerase II promoter [NAS]
- regulation of transcription, DNA-templated [IMP, NAS]
- regulation of translation [TAS]
- segment polarity determination [IMP]
Gene Ontology Molecular Function- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- mRNA 3'-UTR binding [IMP]
- morphogen activity [NAS]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- translation regulator activity [TAS]
- translation repressor activity [IGI]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- mRNA 3'-UTR binding [IMP]
- morphogen activity [NAS]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- translation regulator activity [TAS]
- translation repressor activity [IGI]
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A Drosophila protein-interaction map centered on cell-cycle regulators.
BACKGROUND: Maps depicting binary interactions between proteins can be powerful starting points for understanding biological systems. A proven technology for generating such maps is high-throughput yeast two-hybrid screening. In the most extensive screen to date, a Gal4-based two-hybrid system was used recently to detect over 20,000 interactions among Drosophila proteins. Although these data are a valuable resource for insights into ... [more]
Genome Biol. Dec. 04, 2004; 5(12);R96 [Pubmed: 15575970]
Throughput
- High Throughput
Curated By
- BioGRID