HHF2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SNF5
Gene Ontology Biological Process
- carbon catabolite activation of transcription from RNA polymerase II promoter [IGI]
- chromatin remodeling [IGI, IMP]
- double-strand break repair via homologous recombination [IMP]
- positive regulation of invasive growth in response to glucose limitation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IGI, IMP]
- sucrose catabolic process [IMP]
Gene Ontology Molecular Function
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Histone H3 tail acetylation modulates ATP-dependent remodeling through multiple mechanisms.
There is a close relationship between histone acetylation and ATP-dependent chromatin remodeling that is not fully understood. We show that acetylation of histone H3 tails affects SWI/SNF (mating type switching/ sucrose non fermenting) and RSC (remodels structure of chromatin) remodeling in several distinct ways. Acetylation of the histone H3 N-terminal tail facilitated recruitment and nucleosome mobilization by the ATP-dependent chromatin ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| HHF2 SNF5 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -5.599 | BioGRID | 216897 |
Curated By
- BioGRID